Fat-Dissolving Injection Import: Beyond BNLS? Understanding High-Concentration Deoxycholic Acid Formulations | TASAKI PHAMA

What are Fat Dissolving Injections? Mechanism of Action and Ingredients

Fat dissolving injections are a treatment method aimed at achieving localized fat reduction by decreasing fat cells in specific areas of concern. As they do not involve surgery, they have garnered attention in recent years as a relatively accessible cosmetic procedure. Key ingredients include deoxycholic acid and phosphatidylcholine.

Mechanism of Action: Fat dissolving injections work by directly injecting the medication into the subcutaneous adipose tissue, thereby destroying the cell membranes of fat cells. Fatty acids released from the destroyed fat cells are then expelled from the body via blood vessels and lymphatic vessels. Through this process, the reduction of adipose tissue at the injection site leads to the expected localized fat reduction effect.

Key Ingredients:

• Deoxycholic acid: A type of bile acid that has the effect of destroying the cell membranes of fat cells. It is approved by the FDA (U.S. Food and Drug Administration) as an injectable drug for submental fat reduction.
• Phosphatidylcholine: A major component of soy lecithin, which promotes fat metabolism.
• L-Carnitine: Transports fatty acids to mitochondria, promoting energy production.
• Others: Amino acids, vitamins, and minerals may also be included. These ingredients are used to support fat burning or enhance skin tightening effects.

BNLS vs. High-Concentration Deoxycholic Acid Preparations: Differences in Effects and Ingredients

There are differences in effects and ingredients between BNLS, a well-known fat dissolving injection, and preparations containing high concentrations of deoxycholic acid (such as Kabelline, Cincelar Plus). BNLS primarily uses plant-derived ingredients and is expected to have not only a fat-dissolving effect but also lymphatic circulation promotion and anti-inflammatory effects. In contrast, high-concentration deoxycholic acid preparations specialize in the fat-dissolving action of deoxycholic acid, and are expected to have a higher fat-dissolving effect than BNLS.

BNLS:

• Main Ingredients: Plant-derived ingredients such as Fucus Vesiculosus extract, Aesculus Hippocastanum (Horse Chestnut) Seed Extract, and Juglans Regia (Persian Walnut) Seed Extract.
• Effects: Fat-dissolving action, lymphatic circulation promotion, anti-inflammatory effects.
• Characteristics: Less swelling and pain.

High-Concentration Deoxycholic Acid Preparations (e.g., Kabelline, Cincelar Plus):

• Main Ingredient: Deoxycholic acid.
• Effects: Fat-dissolving action.
• Characteristics: Expected to have a higher fat-dissolving effect than BNLS. May cause more swelling and pain.

About Deoxycholic Acid Concentration

The concentration of deoxycholic acid significantly influences its fat-dissolving effect. Generally, a higher deoxycholic acid concentration leads to a greater fat-dissolving effect. However, higher concentrations also increase the risk of side effects such as swelling and pain, making it crucial to choose an appropriate preparation in consultation with a doctor.

How to Choose Fat Dissolving Injections: Focusing on Kabelline and Cincelar Plus

When choosing a fat dissolving injection, it is important to consider the following points:

• Ingredients: Check the concentration of deoxycholic acid and other active ingredients (e.g., L-Carnitine, phosphatidylcholine).
• Effects: Confirm the expected effects (e.g., fat-dissolving effect, skin tightening effect).
• Safety: Review the risks of side effects and safety data.
• Cost: Ascertain the cost of the treatment.

Kabelline

Kabelline is a fat dissolving injection primarily composed of deoxycholic acid. It is a popular preparation due to its relatively affordable price and expected efficacy. It also has the characteristic of causing less swelling and pain.

Cincelar Plus

Cincelar Plus is a fat dissolving injection formulated with a high concentration of deoxycholic acid. It is expected to provide a higher fat-dissolving effect than Kabelline. However, a disadvantage is that it may cause more swelling and pain.

Other Preparations

In addition, various other fat dissolving injections are available. Understand the characteristics of each preparation and choose the one that suits you best in consultation with a doctor.

Risks and Safety of Fat Dissolving Injections

Fat dissolving injections are a relatively safe treatment method, but risks of side effects do exist. Common side effects include swelling, pain, redness, and bruising. These side effects typically resolve naturally within a few days to several weeks. Rarely, severe side effects such as allergic reactions or infections may occur.

To mitigate risks:

• Choose a reputable medical institution: Select a clinic or hospital with experienced doctors who can provide appropriate treatment.
• Consult thoroughly with your doctor: Communicate your desires and physical constitution to ensure an appropriate preparation and treatment plan are established.
• Adhere to post-procedure care: Follow your doctor’s instructions for proper aftercare.

Fat dissolving injections are one option within aesthetic medicine for body contouring. However, they are not effective for everyone and carry risks. When considering treatment, it is crucial to gather sufficient information and consult with a doctor to make an informed decision.

Safety Precautions:

• Pregnant or breastfeeding women cannot receive fat dissolving injections.
• Individuals with severe medical conditions (such as heart disease, kidney disease, diabetes) must consult with a doctor before undergoing fat dissolving injections.
• Individuals with allergies must consult with a doctor before undergoing fat dissolving injections.

Summary

Fat dissolving injections are one option in aesthetic medicine for localized fat reduction, and preparations primarily composed of deoxycholic acid are particularly expected to be effective in promoting the destruction of fat cells. While they are anticipated to offer a higher fat-dissolving effect compared to preparations mainly composed of plant-derived ingredients like BNLS, risks such as swelling and pain must also be considered. When choosing specific preparations like Kabelline or Cincelar Plus, it is crucial to comprehensively evaluate ingredients, effects, safety, and cost, and make the optimal choice tailored to individual needs through thorough consultation with a doctor. With proper knowledge and understanding, fat dissolving injections have the potential to contribute to beauty and well-being.